# Pharma Engineering

For Engineer By Engineer

• ## Saturday, 2 May 2020

Hiii all ....!!!

This is going to be a general post, there wont be any equations, no formulae but just a 'For Information' post.

Usually we have been operating / seen operating MSGL / SSGL reactors (sometimes these are called enamelled reactors), where molten glass will be lined over metal surfaces with uniform thickness.

There might be some cases during our operations where the enamel / lining will peel off from the metal surface, like operating high basic natured masses for prolonged durations.

One of the cases is Thermal Shock, which is a result of high Î”T i.e., temperature difference between Jacket and inside reaction mass. These kind of scenarios happen when we use extreme utilities like high pressure steam and liquid nitrogen (i know that most of the GL reactors are designed to operate the jacket at ~ -20 to -30 C, but many of us will face this dilemma at some point of career, hence mentioning).

Case - 1:
Here is the maximum allowable Î”T range for jacket when me want to maintain common mass temperature:
 Data Credits: Jennifer Mayo
Let me explain about this, if we want to operate the reaction mass at 20 C, then the extreme range of temperatures are -60 C on lower side and 180 C on higher side.
(You might find that on the scale top, the mass temperature and jacket temperature both will remain same, this is because we shouldn't handle the GL reactors at those temperatures.)

Case - 2:

Now you may get a doubt about the second case, where there will be a minimum and maximum operating temperatures when constant jacket temperature will be maintained (like hubers, julabo systems, Single fluid systems).

Below is the maximum allowable Î”T range for jacket when me want to maintain common jacket temperature:
 Data Credits: Jennifer Mayo
Will give you an example, Lets say the huber set point be 20 C then the mass temperature shouldn't exceed -60 C on lower side and 180 C on higher side.

That's it .....!!!

This post is a 'For Information'.
(For Information always holds some humour in Pharma ðŸ˜‹)

Sharing is caring .......!!!!

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Hi! I am Ajay Kumar Kalva, Currently serving as the CEO of this site, a tech geek by passion, and a chemical process engineer by profession, i'm interested in writing articles regarding technology, hacking and pharma technology.